End Game

My first impulse is to laugh, until the end. Though the text does not say Hamm dies it does imply that's what is going on. It is, to me, a reflection of an all to serious fact: We all die. The play is built around this final ending. And this ending, this death takes place with Hamm being alone. Leading up to his death he knows that ultimately he will cease to be conscious, and it scares him. He asks for medication, for sight, for company to ease his passing, but nothing will ease death. Hamm shows this realization that death is the only result of life when he, says "All he knows is hunger, and cold, and death to crown it all."
Hamm also tells Clov how he will feel when death and time come knocking on his door. He tells him that he will go blind, will be tired, hungry, and then eventually, after the process has been drawn out to be almost unbearable, he will die too, just like Hamm. Infinite emptiness is what awaits in the afterlife, according to Hamm. The total lack of meaning in Hamm's afterlife is the true terror. He may exist, in some spiritual or mental form, maybe. But if he does it will be as a tiny grit in the bigger picture of the next world. Thus, rendering him meaningless and without a purpose or value.
This however is not so different from life now. After Hamm asks, "We're not beginning to...to... mean something?" Clov, finding this funny, says, "Mean something! You and I, mean something! Ah that's a good one!" As Clov sees it he already is meaningless in life, why should death have to have meaning?